GLP-1WeightLoss.org

See what GLP-1 treatment will really cost you.

Current cash prices for Wegovy, Zepbound and the new GLP-1 pills, plus a plain comparison of the online clinics that prescribe them.

  • Manufacturer prices checked October 2026
  • 9 online clinics compared
  • No rankings for sale
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Cost finder

Pick a medicine and dose to see the self-pay price.

Medicine
Dose
$0

Most clinics charge $59–$199 a month. Leave at $0 if your own doctor prescribes.

$0
per month
$0
first 12 months, stepping up one dose a month

Find a clinic that prescribes it

Three ways to get a GLP-1 prescription

Where your prescription comes from decides what you pay. Most people end up using one of these routes.

Your own doctor + insurance

$0–$100+ a month

Cheapest if your plan covers weight-loss drugs, but many plans exclude them or require prior authorization. Ask HR or your insurer about "anti-obesity medication" coverage.

Doctor + manufacturer self-pay

From $149 a month

Any prescriber can send your prescription to LillyDirect or NovoCare Pharmacy for self-pay offers on brand-name medicine. Higher doses can cost more, and some prices require on-time refills. You pay the drug price without a clinic membership.

Online clinic

+ $59–$199 membership

A licensed clinician sees you online, prescribes, and follows up as you raise your dose. Many also check insurance or include coaching. Compare clinics.

How much weight people lost in the trials

Average body-weight loss at the highest studied dose in each medicine's main clinical trial.

Zepbound 15 mgtirzepatide, SURMOUNT-1 trial, 72 weeks
20.9%
Wegovy 7.2 mgsemaglutide, STEP UP trial, 72 weeks
18.7%
Wegovy 2.4 mgsemaglutide, STEP 1 trial, 68 weeks
14.9%
Wegovy pill 25 mgoral semaglutide, OASIS 4 trial, 64 weeks
13.6%
Foundayoorforglipron, ATTAIN-1 trial, 72 weeks
11.1%

These are separate trials with different lengths and participants, so they aren't a head-to-head ranking. Figures use the treatment-regimen estimand (everyone who started, including people who stopped taking the drug). Your results will depend on your dose, how long you stay on treatment and your habits. Sources are listed on each medicine's guide.

Online clinics at a glance

Membership fees only. Medication is billed separately at every clinic below unless noted.

ClinicMembershipCommitmentBest forLink
RoOnline clinic $149/moMonthly or annualPeople who want branded medication and help working out insurance coverage
Branded medsInsurance check
Visit Ro
WeightWatchers Med+Clinic + program $74/mo6 or 12 monthsLowest membership fee with a behavior-change program built in
Lowest feeCoaching included
Visit WeightWatchers
Hims & HersOnline clinic $149/moMonthlyPeople who already use Hims or Hers for other care
App-based
Visit Hims
LifeMDOnline clinic $149/moMonthly or annualPrimary-care style telehealth with an annual weight-loss plan
Annual savings
Visit LifeMD
CalibrateClinic + coaching $199/mo3 months minimumStructured one-on-one coaching on food, sleep, exercise and mindset
1:1 coaching
Visit Calibrate

Fees as published by each clinic, checked October 2026. See all 9 clinics with pros and cons.

Do you qualify?

FDA labels for weight-loss GLP-1s cover adults with a BMI of 30 or more, or 27 or more with a weight-related condition. Check your BMI here; a clinician makes the final decision.

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Common questions

What is a GLP-1 medication?
GLP-1 receptor agonists copy a gut hormone (glucagon-like peptide-1) that tells your brain you're full, slows how fast your stomach empties and helps regulate blood sugar. For weight loss, the FDA-approved options are Wegovy (semaglutide injection), the Wegovy pill (oral semaglutide), Zepbound (tirzepatide, which also acts on the GIP hormone) and Foundayo (orforglipron, a once-daily pill).
Who qualifies for a GLP-1 weight-loss prescription?
The FDA-approved weight-loss labels cover adults with a BMI of 30 or higher, or a BMI of 27 or higher plus at least one weight-related condition such as high blood pressure, type 2 diabetes, high cholesterol or obstructive sleep apnea. A clinician reviews your history to make sure the medicine is safe for you. People with a personal or family history of medullary thyroid cancer or MEN 2 should not take semaglutide or tirzepatide.
How much does a GLP-1 cost without insurance?
As of October 2026, manufacturer self-pay prices start at $149 a month for the starting doses of the Wegovy pill and Foundayo, $199 for the first two months of Wegovy injections (then $349), and $299 a month for the 2.5 mg starting dose of Zepbound. Higher Zepbound doses can be $449 with on-time refills or up to $699 at regular prices. Add any clinic membership or visit fee. See our full cost guide.
Can I get a GLP-1 prescription online?
Yes. Licensed online clinics can evaluate you by video or questionnaire, order labs if needed and send a prescription to a pharmacy or a manufacturer program such as LillyDirect or NovoCare. Expect to share your height, weight, medical history and current medications. Compare online clinics.
Which works better, Wegovy or Zepbound?
In separate trials, people on the top 15 mg dose of Zepbound lost about 21% of their body weight on average over 72 weeks, compared with about 15% on Wegovy 2.4 mg over 68 weeks. In the head-to-head SURMOUNT-5 trial, tirzepatide also produced more weight loss than semaglutide. Individual results vary, and side effects, cost and coverage matter just as much. Read our Zepbound and Wegovy guides.
Are GLP-1 pills as effective as injections?
Slightly less on average. In trials, the Wegovy pill (25 mg) produced about 13.6% average weight loss and Foundayo about 11.1%, compared with about 15–21% for the top injectable doses. Pills avoid needles and the starting doses cost less. See GLP-1 pills compared.

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